Biopharmaceutical research of solid formulations in the educational process using interactive learning methods

• Vaseva Ekaterina M.
• Olga I. Knysh
• Egorova Aleksandra O.

Abstract

In the article "Biopharmacy" discipline teaching methodology at the pharmaceutical faculty of the Tyumen State Medical University using interactive learning methods (small group training, process simulation and simulated clinical situations, project-based learning) is represented. Since the purpose of "Biopharmacy" discipline training consists in formation of theoretical knowledge among students in the field of biopharmaceutical researches and ability of their real-world application, it is proposed to use research project development instead of traditional forms of practical training. That would allow to provide high-quality education by integration of scientific researches and educational process into practice activities. Project development includes 5 stages: preparation, planning, investigation, preparation and presentation of the project, reflection. Nitrofural drug (tablets 0.02 g) was used as an object for setting the model experiment which was tested in vitro by a "Comparative dissolution kinetics test" during the educational process. To conduct an experiment in training conditions equipment for pharmaceutical analysis of solid formulations (Rotating Basket apparatus, friabilator, Reciprocating Basket apparatus, Hardness Tester, etc.) and dialysis medium (purified water) for potency assay in a dialysis medium (photoelectric colorimeter or spectrophotometer) were used.

As a result of the transition from traditional classroom studies to interactive program modes in the course of project work students receive: knowledge on the basis of biopharmaceutics; an idea of pharmaceutical factors and their impact on efficacy; and they acquire knowledge, competence and experience in the field of methods and devices that are used for biopharmaceutical researches. Also the ability to independently integrate previously acquired knowledge in various disciplines into practice activities which are aimed at solving professional problems, as well as the skills of initialization and development of research projects, are being formed.

Keywords:biopharmaceutics, interactive learning methods, model experiment, process simulation, educational and research work of students, project activities

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